Risk Assessment Tools
MAGIC, the MPN Assessment Graphic Interactive Calculator, is a convenient and graphic means to summarize broad clinical experience in assessing overall risk status for myelofibrosis, polycythemia vera and essential thrombocythemia.
The MPN environment creates a special need for patient and caregiver participation.
A look inside MAGIC
The interactive graphic scales.
MAGIC relies on two commonly used and validated scales developed by the International Working Group on Myeloproliferative Neoplasms Research and Treatment (IWG-MRT). Together, the DIPSS (Dynamic International Prognostic Scoring System) and the DIPSS + assess the degree of myelofibrosis risk.*
There are four MF Risk Levels (Low, Intermediate-1, Intermed-2, and High) Each Risk Level carries a mean approximation of overall survival (OS) expressed in years and months. The OS is only a guideline. Mean survival is the midpoint between the number of those who will live longer and those who will die earlier.
Beyond the clinical elements measured by these scales, many other factors influence survival including genetics, environment, co-morbidities, diet, age, lifestyle, epigenetics, geography, occupation, and emotional, social and psychological elements.
The MAGIC results are significant, however, in helping to reveal a patient’s underlying general risk status and can serve as a guide to undertake standard or more aggressive therapies.
MPN Symptom Assessment
The MPN Symptom Assessment scales
MPN Risk Assessment Scales for MF, ET, and PV
An introduction and links to basic research
Common MPN Mutations